Chuck Lorre is a handsome man who, despite his advanced age, maintains a good body. He stands at a height of 5ft. 10inches (1.79m) and weighs approximately 75kg (165 lbs). He has a well maintained athletic body physique with 40 inches as his chest size, 32 inches as his waist size, and 12 inches as his bicep size.
Decades earlier, Lorre struggled with autoimmune disease ulcerative colitis, as well as worry, depression, and anger/fury.