According to the Activision Blizzard Twitch Drops announcement blog, each week will have different cosmetics and start and end times.
The weekly requirements to earn these Twitch Drops demand viewers watch at least three hours of a Diablo IV stream. As a bonus, viewers can watch an additional three hours to obtain more unique cosmetics.
Below is every prize listed on the blog, separated by week and the number of hours a viewer watches.
| Week | Start/End Times | Twitch Drops (3 Hours) | Twitch Drops (6 Hours) |
|---|---|---|---|
| Week 1 | June 5, 4 p.m. — June 11, 11:59 p.m. PDT. | Azurehand Back-Stabber Dagger and Azurehand Heart-Piercer Sword Weapon Recolors. | Matron-Sigil Coffer (Rogue) and Progenitor Favor (Necromancer) Back Trophy. |
| Week 2 | June 12, 12 a.m. —June 18, 11: 59 p.m. PDT. | Azurehand Spell-Slinger Wand Weapon Recolor. | Hellrune Tabernacle Back Trophy. |
| Week 3 | June 19, 12 a.m. — June 25, 11:59 p.m. PDT. | Azurehand Head-Cleaver Weapon Recolor. | Font of the Mother Back Trophy. |
| Week 4 | June 26, 12 a.m. — July 2, 11:59 p.m. PDT. | Azurehand Skull-Crusher. | Matriarch's Mantle Back Trophy. |
From now until July 2 at 11:59 p.m. PDT, players can also get an exclusive Primal Instinct Mount as a reward for gifting two Twitch subscriptions of any tier to an eligible Diablo IV streamer.
You can follow the rather long list of partnered creators that Activision Blizzard has compiled if you're interested.