Stan isn't the only South Park character whose voice has been scrutinized recently. Indeed, fans have also noticed a slight change in Mr. Mackey's voice, as well. The mild-mannered guidance counselor is also voiced by Trey, and some have pointed out that his voice has seemed quite a bit deeper throughout his last few appearances on the show.

In the past, Trey has gotten candid about how health issues have causes him to change the way that he does voices. Screen Rant noted that Trey had to change the way that he voiced Cartman at one point due to damage to his throat.

So, could it be throat damage, a Pro Tools, or some other unknown reason? Until the comedic legends at South Park confirm anything, it's all purely speculation.

Check out new episodes of South Park airing Wednesdays at 8 p.m. EST on Comedy Central.