It's pretty clear that there is no love lost between the over-the-top plastic surgeon and Santina.

But over on his TikTok, fans are demanding answers about where she went.

"Bring Santina back now!" one person blasted the surgeon.

"Pay Santina whatever she wants to come back," implored another commenter.

Others refused to believe that Santina is really gone, with several theorizing her departure is simply an April Fools' Day joke. And several commenters even speculated that Santina was really behind the latest social media post.

Over on her Instagram, one fan put the whole scandal in perspective, saying, "I think we need to accept that Sanrizzle has left Dr. Miami but she is fine, her bank accounts are still gonna be full and slaying without Dr. Miami. The same cannot be said for him though — RIP. He’s nothing without Santina."

And with folks speculating that she was actually fired (since the whole thing seemed "messy"), another fan put it this way: "Plot twist: Nothing happened and she was just ready to flourish on her own!"

Finally, to anyone who is wondering if her leaving is just a ploy to get attention, Santina confirmed via her Instagram stories that she left and doesn't care if someone applies for her job!