It may seem unfair to have picked Riley without reason for the one single bedroom, but that wasn't the case. Apparently, the reason why Riley sleeps alone comes from the fact that she simply wakes up much earlier than her sisters. When she would share a room with any of them, her habit of being up early would disrupt the others. That's why Danielle and Adam Busby decided their daughter needed her own space to wake up as early as she pleased.
Interestingly enough, the original reasoning for giving Riley her own room was that she used to sleep in much longer than her siblings did. So, when they would wake up, they would disrupt her sleep and Riley would be cranky for the day.
Whether waking up early or sleeping in, Riley's unconventional sleeping patterns clearly benefited her in the long run, as she is the only quintuplet who still has her own room. However, there is a new variable in the situation that may change the bedroom configuration in the Busby household yet again.