Kate gave birth to Prince George, who will be next-in-line to the throne after William, in 2013, followed by Princess Charlotte in 2015 and Prince Louis in 2018.
She has spoken about her struggles with severe morning sickness, saying in a podcast that she was "not the happiest of pregnant people".
Prince Harry was often photographed at events with his brother and Kate, seeming to feel relaxed and warm in their company.
When Meghan appeared on the scene, the couples appeared to get on well, prompting predictions that the foursome would become the face of the modern monarchy.
But rumours of a rift began to spread soon after Meghan and Harry's 2018 showpiece wedding at St George's Chapel in Windsor Castle.
The Sun reported in November that year that Meghan had made Kate cry at her daughter Charlotte's bridesmaid dress fitting.
In her bombshell Oprah interview, Meghan claimed the opposite was true but Kate had apologised and sent her flowers.
She complained, however, that Buckingham Palace had never corrected the report.
Critics have accused Britain's unforgiving tabloids of targeting mixed-race Meghan in a way Kate has not faced -- a point not lost on Harry.
In November 2016, soon after their relationship became public, Harry said a "line had been crossed", accusing comment pieces of having "racial undertones".
In the aftermath of the couple's accusation of royal racism, much was made of the contrasting treatment meted out to the two women.