Roumel began her acting career in 2013 with the short film Anaphylaction.In 2015, she starred in the horror drama Creature Lake.In 2017, she had an appearance on the television show Designated Survivor.
She had a guest appearance in the television sitcom Holly Hobbie a year later. Nikki Roumel as Georgia Miller, a teen in Ginny & Georgia.Nikki rose to prominence in 2021 after playing alongside Brianne Howey, Felix Mallard, Katie Douglas, and others in Netflix’s Ginny and Georgia.