While Calzona paused the baby conversation and moved forward, they faced another obstacle in their relationship in Season 7. In the months following the hospital shooting, Arizona received a grant to help care for children in Africa. The move meant Arizona would be living in Africa for three years. Callie, who doesn’t want to travel long distances, begrudgingly agrees to go with Arizona.

Arizona senses Callie doesn’t want to move. Callie’s passive-aggressive attitude causes them to argue on the way to Africa. During the argument, Arizona suggests Callie stay there, and she moves to Africa alone. Callie then gives Arizona an ultimatum, stating, “If you go, we are over!” Arizona replied, “We are standing in the middle of an airport, screaming at each other. We're already over.”