The story of friends turned foes is as old as time itself, and when it came to Biggie and Tupac, it was spurred by one violent night in New York City. While Tupac was pulling up to Quad Recording Studios on Nov. 30, 1994 at the behest of Biggie-affiliate Lil Cease, the California-based rapper was shot, beaten, and robbed. Tupac recovered and later found out that both Biggie and Puff Daddy were inside the studio when the attack went down, which led him to believe that they were behind it all.

Within days of that situation occurring, Tupac was unable to pay a $3 million bail on his head, which led to him being sentenced to a year and a half in prison for sexual abuse. While in prison, Tupac and Death Row Records leader Suge Knight plotted to bring down Bad Boy Records, Puff's label to which Biggie was signed.

While Tupac was in jail, Biggie released the now-infamous track "Who Shot Ya," which many interpreted as a direct diss to Tupac. Biggie denied this on many occasions and maintained that the song was written before the shooting, but Tupac took it as a direct attack and began belittling the Brooklyn rapper. Throughout various raps, Tupac claimed Biggie was behind the shooting, that the younger rapper stole his flow, and even bragged about sleeping with Biggie's wife, Faith Evans.

Despite efforts by Biggie to mediate the situation, Tupac seemingly refused to believe anything less than that his east coast "rival" was secretly plotting against him. Unfortunately, their issues went unresolved as Tupac was shot and killed in a drive-by shooting in Las Vegas on Sept. 7, 1996.

Less than a year later, on March. 9, 1997, Biggie was shot and killed in a drive-by attack in Los Angeles. To this day, both of the rapper's murders are shrouded in mystery, and the story of their beef lives on in infamy amongst the hip hop community.