Spektor is fluent in Russian and reads Hebrew. She has paid tribute to her Russian heritage, quoting the poem "February" by the Russian poet Boris Pasternak in her song "Après Moi", and stating, "I'm very connected to the language and the culture."
Spektor and her family did not return home to Moscow until July 2012, when she toured through Russia in support of her sixth album, What We Saw from the Cheap Seats. She has stated that she used to be vegetarian, though stopped this after touring with The Strokes, who frequently dined on steak.
Spektor married singer-songwriter Jack Dishel in 2011. Formerly a guitarist with the band The Moldy Peaches, Dishel is a member of the band Only Son and duets with Spektor in the song "Call Them Brothers". They had a son in March 2014.
In a 2016 interview on NPR, "Regina Spektor: 'I see my family…In Everybody'", Spektor discusses the experiences and struggles as an immigrant youth in New York have had in contributing to the recent album Remember Us to Life.
