McConaughey played the part of a man diagnosed with HIV/AIDS for the movie Dallas Buyer's Club. The actor lost a whopping thirty-eight pounds for the role.
Right before the five-week shoot kicked off, the actor opened up about his transformation to Hitfix. According to him, getting below 170 pounds was especially difficult.
However, once he got down to about 167 lbs, the next seven pounds just fell right off. Again, getting past 160 was hard, but once he reached 150, he got to his ideal 143 lbs fairly easily.